Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.68 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.68 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211450 | 0.85 | MAPK10 (0.59) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL15647914 | 0.85 | GAA (0.56) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL10650158 | 0.84 | MAPK10 (0.70) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL9207874 | 0.84 | KMT2A (0.59) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL8632192 | 0.84 | KCNQ2 (0.58) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL28600470 | 0.84 | KMT2A (0.66) | MAPK8KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8636686 | 0.84 | MAPK8 (0.67) | MAPK8KMT2AALDH1A1KDM4EKCNQ2 | |
| SCHEMBL10340210 | 0.83 | MAPT (0.71) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL28618234 | 0.83 | ALDH1A1 (0.54) | MAPK10MAPK8MAPK9KMT2AALDH1A1 | |
| SCHEMBL28605594 | 0.81 | MAPK8 (1.00) | MAPK10MAPK8MAPK9KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248399-A | O-amino aromatic amide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-08-13 | — | — | CN | disclosed |