Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.58 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.54 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600470 | 0.88 | KMT2A (0.66) | MAPK8KDM4EALDH1A1LMNAKCNQ2 | |
| SCHEMBL8632192 | 0.88 | KCNQ2 (0.58) | MAPK8KDM4EALDH1A1LMNAKCNQ2 | |
| SCHEMBL28600464 | 0.84 | MAPK10 (0.68) | MAPK8KDM4EALDH1A1KCNQ2KMT2A | |
| SCHEMBL28618234 | 0.84 | ALDH1A1 (0.54) | MAPK8KDM4EALDH1A1LMNAKCNQ2 | |
| SCHEMBL7724422 | 0.81 | MAPT (0.62) | MAPK8ALDH1A1LMNAKCNQ2KCNJ5 | |
| SCHEMBL19710374 | 0.79 | KDM4E (0.52) | MAPK8KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL6579874 | 0.79 | KDM4E (0.52) | MAPK8KDM4EALDH1A1LMNAKCNQ2 | |
| SCHEMBL8636891 | 0.79 | NPC1 (0.64) | MAPK8KDM4EALDH1A1LMNAKCNQ2 | |
| SCHEMBL8639229 | 0.78 | MAPT (0.71) | MAPK8KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL3728253 | 0.78 | PKM (0.59) | MAPK8ALDH1A1KCNQ2KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |