Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.58 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.54 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636686 | 0.88 | MAPK8 (0.67) | KCNQ2KCNJ5KCNJ3MAPK8KMT2A | |
| SCHEMBL28600470 | 0.88 | KMT2A (0.66) | KCNQ2KCNJ5KCNJ3MAPK8KMT2A | |
| SCHEMBL28600464 | 0.84 | MAPK10 (0.68) | KCNQ2MAPK8KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL28618234 | 0.84 | ALDH1A1 (0.54) | KCNQ2KCNJ5KCNJ3MAPK8KMT2A | |
| SCHEMBL7724422 | 0.81 | MAPT (0.62) | KCNQ2KCNJ5KCNJ3MAPK8KMT2A | |
| SCHEMBL6579874 | 0.79 | KDM4E (0.52) | KCNQ2KCNJ5KCNJ3MAPK8KMT2A | |
| SCHEMBL4685295 | 0.76 | KCNJ5 (0.66) | KCNJ5KCNJ3MAPK8LMNASMN1; SMN2 | |
| SCHEMBL11283610 | 0.76 | ALDH1A1 (0.60) | KMT2AMEN1KDM4ELMNAHPGD | |
| SCHEMBL1307889 | 0.75 | MEN1 (0.70) | KCNJ5KCNJ3KMT2AMEN1KDM4E | |
| SCHEMBL28118794 | 0.74 | KMT2A (0.56) | KMT2AMEN1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |