Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873086 | 0.84 | — | — | |
| SCHEMBL433513 | 0.67 | — | — | |
| SCHEMBL3250928 | 0.67 | — | — | |
| SCHEMBL1361284 | 0.67 | — | — | |
| SCHEMBL9833753 | 0.65 | ALDH1A1 (0.56) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL11631395 | 0.64 | — | — | |
| SCHEMBL13462483 | 0.64 | — | — | |
| SCHEMBL18269529 | 0.64 | — | — | |
| SCHEMBL21457914 | 0.64 | — | — | |
| SCHEMBL3815138 | 0.64 | BACE1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979443-A | Continuous preparation method of trifluoromethyl butenone derivative | 浙江蓝天环保高科技股份有限公司 | 2021-06-18 | — | — | CN | disclosed |