Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590553 | 0.91 | ALDH1A1 (0.40) | CA1CA2CA9CA14ALDH1A1 | |
| SCHEMBL28585593 | 0.86 | KDM1A (0.45) | CA1CA2CA9CA14ALDH1A1 | |
| SCHEMBL28591865 | 0.85 | SLC6A2 (0.50) | MAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28589873 | 0.77 | CYP19A1 (0.44) | — | |
| SCHEMBL22622164 | 0.75 | DPP4 (0.46) | ALDH1A1MAOB | |
| SCHEMBL1246669 | 0.72 | SLC6A4 (0.60) | CA1CA2CA9CA14SLC6A2 | |
| SCHEMBL9995792 | 0.72 | MAOB (0.46) | CA1CA2CA9CA14ALDH1A1 | |
| SCHEMBL21694953 | 0.70 | SLC6A2 (0.49) | MAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26939190 | 0.69 | HTR2C (0.49) | CA1CA2CA9CA14MAOB | |
| SCHEMBL28603552 | 0.68 | HTR2C (0.39) | SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794308-B | 1,2,3, 4-tetrahydronaphthalene compound and preparation method and application thereof | 北京大学深圳研究生院 | 2021-07-20 | — | — | CN | disclosed |