Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461769 | 0.78 | MTNR1A (0.50) | HTR2CHTR2BHTR2AOPRM1OPRK1 | |
| SCHEMBL26939190 | 0.71 | HTR2C (0.49) | HTR2CHTR2BHTR2AOPRM1OPRD1 | |
| SCHEMBL28591865 | 0.70 | SLC6A2 (0.50) | HTR2CMEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL11378430 | 0.68 | CHRNB2 (0.44) | HTR2CHTR2BHTR2AMEN1KMT2A | |
| SCHEMBL28600468 | 0.68 | CA1 (0.42) | SLC6A2SLC6A3 | |
| SCHEMBL28585593 | 0.68 | KDM1A (0.45) | — | |
| SCHEMBL8068811 | 0.67 | HTR2C (0.64) | HTR2CHTR2BHTR2ADRD2DRD3 | |
| SCHEMBL13306294 | 0.67 | HTR2C (0.66) | HTR2CHTR2BHTR2ADRD2DRD3 | |
| SCHEMBL31525384 | 0.67 | HTR2C (0.64) | HTR2CHTR2BHTR2ADRD2DRD3 | |
| SCHEMBL16944438 | 0.67 | HTR2C (0.64) | HTR2CHTR2BHTR2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794308-B | 1,2,3, 4-tetrahydronaphthalene compound and preparation method and application thereof | 北京大学深圳研究生院 | 2021-07-20 | — | — | CN | disclosed |