Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625587 | 0.88 | ALDH1A1 (0.54) | KEAP1NFE2L2CRHBPCRHR2COMT | |
| SCHEMBL26332330 | 0.87 | COMT (0.53) | COMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9342188 | 0.83 | PRKCZ (0.48) | KEAP1NFE2L2CRHBPCRHR2IDO1 | |
| SCHEMBL25486860 | 0.83 | ALDH1A1 (0.50) | KEAP1NFE2L2CRHBPCRHR2IDO1 | |
| SCHEMBL22919986 | 0.82 | TP53 (0.43) | MEN1KMT2ANPC1RAB9AADORA2A | |
| SCHEMBL2208987 | 0.82 | ALDH1A1 (0.54) | KEAP1NFE2L2CRHBPCRHR2IDO1 | |
| SCHEMBL23966251 | 0.82 | COMT (0.50) | COMTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28600506 | 0.82 | BRD9 (0.46) | KEAP1NFE2L2CRHBPCRHR2IDO1 | |
| SCHEMBL24901300 | 0.80 | ALDH1A1 (0.52) | KEAP1NFE2L2CRHBPCRHR2IDO1 | |
| SCHEMBL27863304 | 0.79 | IDO1 (0.54) | KEAP1NFE2L2CRHBPCRHR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053550-B | Synthesis method of benzindole derivative | 陕西科技大学 | 2021-06-25 | — | — | CN | disclosed |