SCHEMBL9342188

SCHEMBL9342188

Nc1ccc(-c2ccc(N)c3ccccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.48
KEAP1 Q14145 2/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
NFE2L2 Q16236 1/20 0.48
CYP3A4 P08684 5/20 0.48
TDP1 Q9NUW8 5/20 0.48
HSD17B10 Q99714 4/20 0.48
TAAR1 Q96RJ0 1/20 0.48
IDO1 P14902 2/20 0.46
EP300 Q09472 2/20 0.46
KAT8 Q9H7Z6 2/20 0.46
HDAC3 O15379 1/20 0.46
KAT2B Q92831 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
HPGD P15428 2/20 0.46
TP53 P04637 1/20 0.43
CHEK1 O14757 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712565 0.91 HSD17B10 (0.57) PRKCZCYP3A4TDP1HSD17B10TAAR1
SCHEMBL29897033 0.91 HSD17B10 (0.57) PRKCZCYP3A4TDP1HSD17B10TAAR1
SCHEMBL15139201 0.88 HSD17B10 (0.55) PRKCZCYP3A4TDP1HSD17B10TAAR1
SCHEMBL25486860 0.86 ALDH1A1 (0.50) KEAP1CRHBPCRHR2NFE2L2CYP3A4
SCHEMBL21557168 0.86 HSD17B10 (0.67) PRKCZCYP3A4TDP1HSD17B10TAAR1
SCHEMBL2208987 0.86 ALDH1A1 (0.54) KEAP1CRHBPCRHR2NFE2L2CYP3A4
SCHEMBL24901300 0.84 ALDH1A1 (0.52) KEAP1CRHBPCRHR2NFE2L2CYP3A4
SCHEMBL28600508 0.83 KEAP1 (0.45) KEAP1CRHBPCRHR2NFE2L2CYP3A4
SCHEMBL27863304 0.83 IDO1 (0.54) KEAP1CRHBPCRHR2NFE2L2CYP3A4
SCHEMBL28596715 0.82 IDO1 (0.44) KEAP1CRHBPCRHR2NFE2L2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355575-B1 Method of preventing polymer scale formation SHINETSU CHEMICAL CO (JP) 1994-11-02 EP claimed
US-5298220-A Forming a coating of a solution containing anioic and cationic dyes and water insoluble organonitrogen compound, drying SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-03-29 US claimed
US-5196164-A During addition polymerization, wall coating of anionic dye and cationic dye and organonitrogen compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US claimed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP claimed
EP-3561892-B1 ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO LTD (KR) 2023-05-10 EP disclosed
EP-3561892-A1 ORGANIC LIGHT-EMITTING DEVICE Heesung Material Ltd. (KR) 2019-10-30 EP disclosed
WO-2016204394-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-12-22 WO disclosed
WO-2011126224-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-10-13 WO disclosed
EP-0355575-B1 Method of preventing polymer scale formation SHINETSU CHEMICAL CO (JP) 1994-11-02 EP disclosed
US-5298220-A Forming a coating of a solution containing anioic and cationic dyes and water insoluble organonitrogen compound, drying SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-03-29 US disclosed
US-5196164-A During addition polymerization, wall coating of anionic dye and cationic dye and organonitrogen compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US disclosed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP disclosed