Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 4/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL17713174 | 1.00 | INMT (0.78) | INMTUSP2SMN1; SMN2TDP1HRH1 | |
| SCHEMBL2734323 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL17417853 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL3047 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL6853620 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL10601682 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL16583523 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL2401189 | 0.88 | INMT (1.00) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| Iodide SCHEMBL23365018 | 0.86 | INMT (0.95) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 | |
| Fluoride SCHEMBL14777947 | 0.86 | INMT (0.95) | INMTUSP2SMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311946-A1 | Solid Phase Peptide for the Production of Goserelin | MALLINCKRODT INC. (US) | 2010-12-09 | — | — | US | claimed |
| US-8742028-B2 | Solid support for Fmoc-solid phase synthesis of peptide acids | MALLINCKRODT LLC (US) | 2014-06-03 | — | — | US | disclosed |
| EP-2215106-B1 | INDOLE GRAFTED SOLID SUPPORT FOR FMOC-SOLID PHASE PEPTIDE SYNTHESIS | MALLINCKRODT LLC (US) | 2013-02-13 | — | — | EP | disclosed |
| EP-2427474-A1 | SOLID SUPPORT FOR FMOC-SOLID PHASE SYNTHESIS OF PEPTIDE ACIDS | Mallinckrodt LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011011342-A1 | SYNTHESIS OF DESMOPRESSIN | MALLINCKRODT INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100311946-A1 | Solid Phase Peptide for the Production of Goserelin | MALLINCKRODT INC. (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141276-A1 | SOLID PHASE PEPTIDE SYNTHESIS PROCESS FOR THE PRODUCTION OF GOSERELIN | MALLINCKRODT INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20100286359-A1 | Solid Support for FMOC-Solid Phase Synthesis of Peptide Acids | MALLINCKRODT INC. (US) | 2010-11-11 | — | — | US | disclosed |
| WO-2010129520-A1 | SOLID SUPPORT FOR FMOC-SOLID PHASE SYNTHESIS OF PEPTIDE ACIDS | MALLINCKRODT INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| EP-2215106-A1 | INDOLE GRAFTED SOLID SUPPORT FOR FMOC-SOLID PHASE PEPTIDE SYNTHESIS | Mallinckrodt Inc. (US) | 2010-08-11 | — | — | EP | disclosed |
| US-7714063-B2 | Solid support for Fmoc-solid phase synthesis of peptides | MALLINCKRODT INC. (US) | 2010-05-11 | — | — | US | disclosed |
| WO-2009064637-A1 | INDOLE GRAFTED SOLID SUPPORT FOR FMOC-SOLID PHASE PEPTIDE SYNTHESIS | MALLINCKRODT INC. (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20090131587-A1 | Solid Support for Fmoc-Solid Phase Synthesis of Peptides | MALLINCKRODT INC. (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311946-A1 | Solid Phase Peptide for the Production of Goserelin | GCG, GNRHR, GIPR | INMT 539/4885USP2 1800/4885SMN1; SMN2 3188/4885 |
| US-20090131587-A1 | Solid Support for Fmoc-Solid Phase Synthesis of Peptides | MAX, PTMS, ANPEP | INMT 2137/4885USP2 3374/4885SMN1; SMN2 1505/4885 |
| US-20100286359-A1 | Solid Support for FMOC-Solid Phase Synthesis of Peptide Acids | MAX, NPPA, PTMS | INMT 2641/4885USP2 3442/4885SMN1; SMN2 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.