Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967919 | 0.84 | MCL1 (0.62) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL7682529 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL7682886 | 0.84 | PTGS2 (0.54) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL17967806 | 0.84 | BCHE (0.48) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL584257 | 0.82 | ATM (0.65) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL5527880 | 0.82 | ERN1 (0.61) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL24456083 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL1249146 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL5522283 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL14521043 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567445-B | 2-phenyl-3H-imidazo [4,5-B ] pyridine derivatives useful as inhibitors of mammalian tyrosine kinase ROR1 activity | 坎塞拉有限公司 | 2021-06-29 | — | — | CN | disclosed |