Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600675 | 0.85 | MCL1 (0.48) | MCL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL27983605 | 0.84 | MCL1 (0.47) | MCL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28603794 | 0.82 | MCL1 (0.51) | MCL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28614724 | 0.82 | MCL1 (0.51) | MCL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL12111459 | 0.82 | NPC1 (0.57) | MAPTKMT2AMEN1ALDH1A1CASP3 | |
| SCHEMBL29249014 | 0.80 | UTS2R (0.46) | MCL1 | |
| SCHEMBL22500487 | 0.80 | CASP3 (0.57) | MAPTKMT2AMEN1ALDH1A1CASP3 | |
| SCHEMBL22372314 | 0.80 | MAPT (0.53) | MAPTKMT2AMEN1ALDH1A1CASP3 | |
| SCHEMBL20354607 | 0.80 | KMT2A (0.53) | MAPTKMT2AMEN1ALDH1A1CASP3 | |
| SCHEMBL28919836 | 0.78 | IMPDH2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227074-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods | 凌科药业(杭州)有限公司 | 2021-08-06 | — | — | CN | disclosed |