Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603794 | 1.00 | MCL1 (0.51) | MCL1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28919836 | 0.84 | IMPDH2 (0.56) | — | |
| SCHEMBL28601403 | 0.83 | MCL1 (0.49) | MCL1MAPTALDH1A1L3MBTL1UTS2R | |
| SCHEMBL28600679 | 0.82 | MCL1 (0.50) | MCL1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL14064862 | 0.82 | MCL1 (0.48) | MCL1CASP3UTS2R | |
| SCHEMBL8614667 | 0.82 | MEN1 (0.51) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28600675 | 0.80 | MCL1 (0.48) | MCL1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12111459 | 0.80 | NPC1 (0.57) | MAPTMEN1ALDH1A1KMT2ACASP3 | |
| SCHEMBL27983605 | 0.79 | MCL1 (0.47) | MCL1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL4760948 | 0.78 | UTS2R (0.54) | MAPTMEN1ALDH1A1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227074-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods | 凌科药业(杭州)有限公司 | 2021-08-06 | — | — | CN | disclosed |