Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442218 | 0.82 | CYP11B1 (0.48) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28600768 | 0.82 | MAPT (0.44) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28988626 | 0.80 | ALDH1A1 (0.36) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7600910 | 0.79 | MAPT (0.50) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL13917260 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KDM4EUSP2SLC6A2 | |
| SCHEMBL28596598 | 0.78 | PTPN1 (0.46) | ALDH1A1USP2TSHRCYP3A4CYP2D6 | |
| SCHEMBL28988609 | 0.78 | PTPN1 (0.59) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11974293 | 0.77 | MAOB (0.51) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL13680763 | 0.76 | MAPT (0.44) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL17876375 | 0.76 | MAPT (0.47) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-B | Method for preparing 3-substituted chromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-03-05 | — | — | CN | disclosed |
| CN-115974825-A | Method for preparing 3-substituted chromanone through metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-112898259-B | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-112898259-A | Method for preparing 3-substituted chromanone through nonmetal catalytic hydrogenation | 中国科学院化学研究所 | 2021-06-04 | — | — | CN | disclosed |