Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700653 | 0.86 | ALDH1A1 (0.55) | MAPTALDH1A1HPGDUSP2TSHR | |
| SCHEMBL19099778 | 0.85 | MAPT (0.49) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL7600910 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL28477936 | 0.79 | ALDH1A1 (0.47) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28900624 | 0.79 | CYP11B1 (0.51) | MAPTSMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL2108389 | 0.79 | KDM4E (0.61) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28470248 | 0.79 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL2109107 | 0.78 | RAB9A (0.61) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL17876373 | 0.78 | PTPN1 (0.45) | MAPTSMN1; SMN2ALOX15KMT2AALDH1A1 | |
| SCHEMBL13640741 | 0.76 | KDM4E (0.62) | MAPTSMN1; SMN2ALOX15KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406075-A | Silicon-containing polycyclic chromone skeleton compound, preparation method and application thereof | 遵义医科大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-118255735-A | Preparation method of cyclopenta [ b ] chromone compound | 遵义医科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-114560838-B | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-112898256-B | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-111732567-B | Chromone framework-containing polycyclic compound, and preparation method and application thereof | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-113149948-B | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114560838-A | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113149948-A | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-112898256-A | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-111732567-A | Chromone framework-containing polycyclic compound, and preparation method and application thereof | 遵义医科大学 | 2020-10-02 | — | — | CN | disclosed |
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | VAT1, NQO1, VARS1 | MAPT 1736/4885SMN1; SMN2 3336/4885ALOX15 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.