Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653979 | 0.67 | MEN1 (0.33) | MEN1KMT2AMAOALMNAHTT | |
| SCHEMBL13391693 | 0.65 | MEN1 (0.32) | MEN1KMT2AMAOALMNAHTT | |
| SCHEMBL28481228 | 0.64 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL4610872 | 0.63 | NPC1 (0.39) | MEN1KMT2AMAOALMNAHTT | |
| SCHEMBL382451 | 0.63 | NPC1 (0.35) | MEN1KMT2AMAOALMNAHTT | |
| Water SCHEMBL11162060 | 0.62 | NPC1 (0.34) | MEN1KMT2AMAOALMNAHTT | |
| SCHEMBL29367325 | 0.56 | ALDH1A1 (0.77) | MEN1KMT2AMAOALMNAHTT | |
| SCHEMBL145891 | 0.56 | ALDH1A1 (0.77) | MEN1KMT2AMAOALMNAHTT | |
| SCHEMBL320609 | 0.55 | MEN1 (1.00) | MEN1KMT2ALMNAACHEALDH1A1 | |
| SCHEMBL27981 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112973456-B | Two-dimensional metal organic framework nanosheet film, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-05-10 | — | — | CN | disclosed |
| CN-112973456-A | Two-dimensional metal organic framework nanosheet film, and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2021-06-18 | — | — | CN | disclosed |