Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000768 | 0.88 | KMT2A (0.47) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL28846397 | 0.80 | ACHE (0.49) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL28597878 | 0.80 | KMT2A (0.41) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL27714304 | 0.80 | ACHE (0.49) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL27484827 | 0.75 | CYP4F2 (0.42) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL1995725 | 0.74 | CYP4F2 (0.49) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL29131729 | 0.74 | KMT2A (0.48) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL1995471 | 0.74 | ESR1 (0.40) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL1787665 | 0.74 | KMT2A (0.53) | KMT2AESR1HIF1ASMN1; SMN2RECQL | |
| SCHEMBL1996079 | 0.74 | BCL9 (0.46) | KMT2AKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |