Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763915 | 0.85 | MAPT (0.43) | KMT2ACA1CA2CA4MAPT | |
| SCHEMBL1998865 | 0.84 | ESR1 (0.42) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL2000685 | 0.84 | ALOX15 (0.41) | KMT2ACA1CA2CA4MAPT | |
| SCHEMBL1401782 | 0.82 | HIF1A (0.41) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL2000768 | 0.82 | KMT2A (0.47) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL10180980 | 0.82 | KMT2A (0.39) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL17373963 | 0.82 | VCAM1 (0.38) | KMT2ACA1CA2CA4MAPT | |
| SCHEMBL17337902 | 0.82 | KMT2A (0.40) | KMT2ACA1CA2CA4MAPT | |
| SCHEMBL1998098 | 0.81 | KMT2A (0.44) | RECQLKMT2ASMN1; SMN2KDM4EALOX15 | |
| Fluoride SCHEMBL27712387 | 0.80 | HIF1A (0.39) | ESR1HIF1ARECQLKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| EP-4559901-A1 | RADIOLABELED ACTIVATED ESTER AND PRECURSOR THEREOF | Institute of Science Tokyo (JP) | 2025-05-28 | — | — | EP | disclosed |
| US-20230364251-A1 | METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES | CIDARA THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| US-11793895-B2 | Residualizing linkers and uses thereof | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION | 2023-10-24 | — | — | US | disclosed |
| CN-116897054-A | anti-HER 2 immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116744978-A | anti-HER 2 immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116723866-A | anti-PD-L1 immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-20230273194-A1 | NON-INVASIVE METHOD FOR DETECTION OF ENZYME ACTIVITY IN VIVO, SUBSTRATES AND A DEVICE THEREFORE | ETH Zürich (CH) | 2023-08-31 | — | — | US | disclosed |
| US-20230273194-A1 | NON-INVASIVE METHOD FOR DETECTION OF ENZYME ACTIVITY IN VIVO, SUBSTRATES AND A DEVICE THEREFORE | ETH Zürich (CH) | 2023-08-31 | — | — | US | disclosed |
| CN-116635084-A | anti-CEA immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-08-22 | — | — | CN | disclosed |
| US-20170355731-A1 | AMATOXIN DERIVATIVES AND CONJUGATES THEREOF AS INHIBITORS OF RNA POLYMERASE | NOVARTIS INSTITUTE FOR FUNCTIONAL GENOMICS, INC., DBA GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION | 2017-12-14 | — | — | US | disclosed |
| WO-2017191579-A1 | AMATOXIN DERIVATIVES AND CONJUGATES THEREOF AS INHIBITORS OF RNA POLYMERASE | NOVARTIS AG (CH) | 2017-11-09 | — | — | WO | disclosed |
| US-9751953-B2 | Antibodies to risperidone haptens and use thereof | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-05 | — | — | US | disclosed |
| WO-2015073575-A2 | RESIDUALIZING LINKERS AND USES THEREOF | CENTRE FOR PROBE DEVELOPMENT AND COMMERCIALIZATION (CA) | 2015-05-21 | — | — | WO | disclosed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| CN-102186921-B | Fluorine-containing copolymer composition and process for production thereof | ASAHI GLASS CO LTD | 2014-01-15 | — | — | CN | disclosed |
| EP-2338935-B1 | FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF | ASAHI GLASS CO LTD (JP) | 2012-12-12 | — | — | EP | disclosed |
| CN-102186921-A | Fluorine-containing copolymer composition and process for production thereof | ASAHI GLASS CO LTD | 2011-09-14 | — | — | CN | disclosed |
| US-20110172336-A1 | FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2338935-A1 | FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355731-A1 | AMATOXIN DERIVATIVES AND CONJUGATES THEREOF AS INHIBITORS OF RNA POLYMERASE | RNGTT, RNASE1, RNMT | ESR1 4726/4885HIF1A 2275/4885RECQL 1218/4885 |
| US-11793895-B2 | Residualizing linkers and uses thereof | CD44, CD47, MTCL3 | ESR1 3474/4885HIF1A 3834/4885RECQL 3973/4885 |
| US-20230364251-A1 | METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES | DNPEP, NPEPPS, DHFR | ESR1 4015/4885HIF1A 2560/4885RECQL 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.