Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714304 | 0.87 | ACHE (0.49) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL16922693 | 0.86 | SLC6A4 (0.43) | ACHEKMT2ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL1787665 | 0.84 | KMT2A (0.53) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL25385502 | 0.83 | ACHE (0.59) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL15605755 | 0.82 | KMT2A (0.46) | KMT2ASMN1; SMN2ALDH1A1HSD17B10SLC6A4 | |
| SCHEMBL1824842 | 0.81 | LMNA (0.47) | ACHEKMT2ASMN1; SMN2ELANEKDM4E | |
| SCHEMBL28601319 | 0.80 | KMT2A (0.41) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL3218515 | 0.79 | ACHE (0.48) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL6446983 | 0.79 | RARB (0.49) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL3932133 | 0.78 | KMT2A (0.50) | ACHEKMT2ASMN1; SMN2ESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945560-A | GPR119 agonists | 卡尔优普公司 | 2022-08-26 | — | — | CN | disclosed |