Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500153 | 0.78 | MEN1 (0.45) | ALDH1A1DRD3CHRM3CHRM2ADRA2B | |
| SCHEMBL23898801 | 0.76 | ALDH1A1 (0.43) | ALDH1A1DRD3CHRM2ADRA2BSIGMAR1 | |
| SCHEMBL23886210 | 0.76 | ALDH1A1 (0.43) | ALDH1A1DRD3CHRM2ADRA2BSIGMAR1 | |
| SCHEMBL25191941 | 0.76 | ALDH1A1 (0.43) | ALDH1A1DRD3CHRM2ADRA2BSIGMAR1 | |
| SCHEMBL11805982 | 0.75 | CHRM1 (0.50) | SLC6A3ALDH1A1DRD3CHRM3CHRM1 | |
| SCHEMBL25187516 | 0.74 | ALDH1A1 (0.42) | ALDH1A1DRD3CHRM2ADRA2BSIGMAR1 | |
| SCHEMBL25264913 | 0.74 | ALDH1A1 (0.42) | ALDH1A1DRD3CHRM2ADRA2BSIGMAR1 | |
| SCHEMBL277403 | 0.73 | CHRM1 (0.54) | SLC6A3ALDH1A1DRD3CHRM3CHRM1 | |
| SCHEMBL15362967 | 0.72 | SLC6A4 (0.37) | SLC6A4SLC6A3ALDH1A1DRD3CHRM3 | |
| SCHEMBL29008687 | 0.71 | SLC6A3 (0.47) | SLC6A4SLC6A3DRD3CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024434-A | Preparation method of brivaracetam intermediate | 上海科胜药物研发有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-111333563-A | Preparation method of brivaracetam intermediate | 上海科胜药物研发有限公司 | 2020-06-26 | — | — | CN | disclosed |