Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602496 | 0.93 | JAK3 (0.39) | JAK3RAB9AHTTLIG1MAPT | |
| SCHEMBL28608069 | 0.90 | JAK3 (0.42) | JAK3RAB9AMAPTNPC1KMT2A | |
| SCHEMBL28606032 | 0.90 | GRIK1 (0.41) | JAK3LIG1KMT2AGRIK1IDH1 | |
| SCHEMBL28599139 | 0.89 | GRIK1 (0.40) | RAB9AHTTLIG1NPC1KMT2A | |
| SCHEMBL28614923 | 0.89 | GRIK1 (0.40) | RAB9AHTTLIG1NPC1KMT2A | |
| SCHEMBL28611051 | 0.88 | MAPT (0.42) | JAK3RAB9AMAPTGRIK1 | |
| SCHEMBL28606036 | 0.88 | JAK3 (0.39) | JAK3RAB9AHTTMAPTNPC1 | |
| SCHEMBL28599093 | 0.87 | LIG1 (0.39) | RAB9AHTTLIG1MAPTKMT2A | |
| SCHEMBL28606070 | 0.86 | GRIK1 (0.42) | RAB9ALIG1MAPTNPC1KMT2A | |
| SCHEMBL28612432 | 0.86 | RAB9A (0.42) | JAK3RAB9AMAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |