Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521280 | 0.84 | ACHE (0.44) | LPLLIPGACHEHIF1ABCHE | |
| SCHEMBL24142282 | 0.81 | LIPG (0.54) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL22418560 | 0.80 | AAK1 (0.51) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL311872 | 0.79 | CA1 (0.55) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14242308 | 0.78 | CA9 (0.60) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2730662 | 0.77 | CA1 (0.58) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL28811198 | 0.77 | CA1 (0.54) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL25988979 | 0.76 | CA1 (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL18124825 | 0.76 | CA1 (0.53) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL118986 | 0.75 | CA1 (0.51) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108136044-B | Imide-based proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2021-08-10 | — | — | CN | disclosed |