Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.44 |
| ▸ | LPL | P06858 | 8/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730662 | 0.83 | CA1 (0.58) | CA1CA2CA9F11AAK1 | |
| SCHEMBL311872 | 0.81 | CA1 (0.55) | CA1CA2CA9F11AAK1 | |
| SCHEMBL18124825 | 0.78 | CA1 (0.53) | CA1CA2CA9F11AAK1 | |
| SCHEMBL15356539 | 0.77 | CA1 (0.51) | CA1CA2CA9F11AAK1 | |
| SCHEMBL28601588 | 0.77 | LPL (0.49) | CA1CA2CA9AAK1LIPG | |
| SCHEMBL28513571 | 0.77 | CA1 (0.51) | CA1CA2CA9F11AAK1 | |
| SCHEMBL28339407 | 0.76 | PDE4A (0.43) | CA1CA2CA9F11AAK1 | |
| SCHEMBL5956627 | 0.76 | CA1 (0.54) | CA1CA2CA9F11AAK1 | |
| SCHEMBL25988979 | 0.75 | CA1 (0.47) | CA1CA2CA9F11AAK1 | |
| SCHEMBL3448477 | 0.75 | CA1 (0.53) | CA1CA2CA9F11AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846013-A | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2022-08-02 | — | — | CN | disclosed |