SCHEMBL28601663

SCHEMBL28601663

COC(=O)Nc1nc2ccc(S)cc2[nH]1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 9/20 0.63
CYP1A2 P05177 6/20 0.63
HIF1A Q16665 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
KDR P35968 3/20 0.63
ALDH1A1 P00352 3/20 0.63
ABL1 P00519 2/20 0.63
CYP2C9 P11712 2/20 0.63
HTT P42858 2/20 0.63
CYP2C19 P33261 1/20 0.63
ABCC4 O15439 1/20 0.63
USP2 O75604 1/20 0.63
TUBB4A P04350 7/20 0.62
TUBB P07437 7/20 0.62
TUBA3C P0DPH7 7/20 0.62
TUBA1B P68363 7/20 0.62
TUBA4A P68366 7/20 0.62
TUBB4B P68371 7/20 0.62
TUBB3 Q13509 7/20 0.62
TUBB2A Q13885 7/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11087273 0.89 LMNA (0.53) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL30700091 0.84 LMNA (0.64) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL11402164 0.84 TUBB4A (0.76) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL5037530 0.84 LMNA (0.64) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL11171725 0.83 LMNA (0.63) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL6126460 0.83 LMNA (0.63) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL5351444 0.83 LMNA (0.63) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL10727499 0.82 LMNA (0.55) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL11373040 0.82 LMNA (0.77) LMNACYP1A2HIF1ASMN1; SMN2KDR
SCHEMBL18762324 0.82 LMNA (0.77) LMNACYP1A2HIF1ASMN1; SMN2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707831-A Synthesis of albenzene method for preparing dazole 河北美荷药业有限公司 2025-03-28 CN claimed
CN-119776216-A Application of bacillus megatherium in synthesis of 5-aminobenzimidazole-2-methyl carbamate 河北美荷药业有限公司 2025-04-08 CN disclosed
CN-119707831-A Synthesis of albenzene method for preparing dazole 河北美荷药业有限公司 2025-03-28 CN disclosed
CN-113186570-B Piston rod surface treatment process 江苏新合益机械有限公司 2021-12-28 CN disclosed
CN-113186570-A Piston rod surface treatment process 江苏新合益机械有限公司 2021-07-30 CN disclosed