Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970829 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNA | |
| SCHEMBL14368338 | 0.68 | KDM4E (0.58) | ALDH1A1MAPTHSD17B10NPC1KDM4E | |
| SCHEMBL29021863 | 0.68 | RAB9A (0.47) | ALDH1A1MAPTHSD17B10NPC1KDM4E | |
| SCHEMBL11821279 | 0.67 | ADRB2 (0.46) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL9093912 | 0.66 | ALDH1A1 (0.46) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL10402770 | 0.64 | MEN1 (0.63) | ALDH1A1MAPTHSD17B10NPC1KDM4E | |
| SCHEMBL9093822 | 0.64 | ALDH1A1 (0.38) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL28127567 | 0.61 | — | — | |
| SCHEMBL14368329 | 0.60 | — | — | |
| SCHEMBL4964168 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061130-B | Preparation method of arotinolol hydrochloride | 山东中健康桥制药有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-113061130-A | Preparation method of arotinolol hydrochloride | 山东中健康桥制药有限公司 | 2021-07-02 | — | — | CN | claimed |
| CN-113061130-B | Preparation method of arotinolol hydrochloride | 山东中健康桥制药有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-113061130-B | Preparation method of arotinolol hydrochloride | 山东中健康桥制药有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-113061130-A | Preparation method of arotinolol hydrochloride | 山东中健康桥制药有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-113061130-A | Preparation method of arotinolol hydrochloride | 山东中健康桥制药有限公司 | 2021-07-02 | — | — | CN | disclosed |