Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005457 | 0.79 | PKM (0.61) | SLC6A2SLC6A4SLC6A3PKMGAA | |
| SCHEMBL29455856 | 0.78 | ATM (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21815505 | 0.78 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1CYP2C9 | |
| SCHEMBL22117597 | 0.78 | ATM (0.39) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL8447638 | 0.72 | HSD17B10 (0.33) | — | |
| SCHEMBL13181757 | 0.70 | MMP2 (0.49) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL9836283 | 0.69 | ALDH1A1 (0.39) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8501839 | 0.68 | ESR1 (0.39) | ALDH1A1 | |
| SCHEMBL12466963 | 0.68 | PIK3CD (0.49) | PKMGAACYP2C9CYP2C19 | |
| SCHEMBL21989804 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358578-B | Antibodies to transferrin receptor and methods of use thereof | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-107001473-B | Anti-transferrin receptor antibodies and methods of use | 豪夫迈·罗氏有限公司 | 2021-07-09 | — | — | CN | disclosed |