Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344799 | 0.91 | HIF1A (1.00) | HIF1ANPC1RAB9AFAAH | |
| SCHEMBL28601911 | 0.89 | HIF1A (0.85) | HIF1ANPC1RAB9AFAAHMCHR1 | |
| SCHEMBL28608835 | 0.89 | HIF1A (0.85) | HIF1ANPC1RAB9AFAAH | |
| SCHEMBL28614480 | 0.88 | HIF1A (0.79) | HIF1AFAAHGCGR | |
| SCHEMBL28596560 | 0.88 | HIF1A (0.83) | HIF1ANPC1RAB9AFAAH | |
| SCHEMBL28347634 | 0.88 | HIF1A (1.00) | HIF1ANPC1RAB9AFAAH | |
| SCHEMBL28607757 | 0.86 | HIF1A (1.00) | HIF1AALDH1A1NPC1RAB9AFAAH | |
| SCHEMBL28345384 | 0.84 | HIF1A (0.88) | HIF1ANPC1RAB9AGCGR | |
| SCHEMBL28344792 | 0.83 | HIF1A (0.76) | HIF1AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28598211 | 0.82 | HIF1A (1.00) | HIF1ANPC1RAB9AGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |