Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.85 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.59 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GCGR | P47871 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344799 | 0.92 | HIF1A (1.00) | HIF1AEGLN1NPC1RAB9AMAPT | |
| SCHEMBL28608835 | 0.90 | HIF1A (0.85) | HIF1AEGLN1NPC1RAB9AFAAH | |
| SCHEMBL28596560 | 0.89 | HIF1A (0.83) | HIF1AEGLN1NPC1RAB9ACNR1 | |
| SCHEMBL28601903 | 0.89 | HIF1A (0.83) | HIF1ANPC1RAB9AGCGRMCHR1 | |
| SCHEMBL28347634 | 0.89 | HIF1A (1.00) | HIF1AEGLN1NPC1RAB9AFAAH | |
| SCHEMBL28607757 | 0.87 | HIF1A (1.00) | HIF1AEGLN1NPC1RAB9AFAAH | |
| SCHEMBL28601917 | 0.86 | HIF1A (1.00) | HIF1AEGLN1NPC1RAB9AMAPT | |
| SCHEMBL7703654 | 0.85 | HIF1A (0.72) | HIF1ANPC1RAB9A | |
| SCHEMBL28344792 | 0.84 | HIF1A (0.76) | HIF1ANPC1RAB9AMAPTLMNA | |
| SCHEMBL28598668 | 0.83 | HIF1A (1.00) | HIF1AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |