Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344799 | 0.87 | HIF1A (1.00) | HIF1ARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28608835 | 0.84 | HIF1A (0.85) | HIF1ARAB9ANPC1TAAR1FAAH | |
| SCHEMBL28601911 | 0.84 | HIF1A (0.85) | HIF1ARAB9ANPC1MAPTMEN1 | |
| SCHEMBL8824716 | 0.83 | RAB9A (0.65) | HIF1ARAB9ASMN1; SMN2NPC1TAAR1 | |
| SCHEMBL28347634 | 0.83 | HIF1A (1.00) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28596560 | 0.83 | HIF1A (0.83) | HIF1ARAB9ANPC1MAPTFAAH | |
| SCHEMBL28601903 | 0.83 | HIF1A (0.83) | HIF1ARAB9ANPC1ALDH1A1FAAH | |
| SCHEMBL28607757 | 0.82 | HIF1A (1.00) | HIF1ARAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL28601907 | 0.78 | HIF1A (0.81) | HIF1ARAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL6962971 | 0.78 | SMN1; SMN2 (0.89) | RAB9ASMN1; SMN2NPC1TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-110407824-A | Aryl methanamide compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV ANHUI MEDICAL | 2019-11-05 | — | — | CN | disclosed |