Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703958 | 0.93 | IRAK4 (0.66) | HDAC6HPGDTSHRHDAC2TP53 | |
| SCHEMBL28348018 | 0.91 | HPGD (0.63) | HDAC6HPGDHDAC2MAPTALDH1A1 | |
| SCHEMBL28601973 | 0.85 | HDAC6 (0.69) | HDAC6HPGDTSHRHDAC2TP53 | |
| SCHEMBL28344825 | 0.84 | IRAK4 (0.68) | HDAC6HPGDTSHRHDAC2TP53 | |
| SCHEMBL17175809 | 0.81 | IRAK4 (0.69) | HDAC6HPGDHDAC2TP53MAPT | |
| SCHEMBL28970478 | 0.80 | HDAC6 (0.78) | HDAC6HDAC2MAPTIRAK4ALDH1A1 | |
| SCHEMBL11114421 | 0.80 | HPGD (0.67) | HDAC6HPGDMAPTTLR7RAB9A | |
| SCHEMBL3477450 | 0.79 | HDAC6 (0.67) | HDAC6HDAC2MAPTIRAK4TLR7 | |
| SCHEMBL2113234 | 0.79 | HDAC6 (0.67) | HDAC6HDAC2TP53MAPTIRAK4 | |
| SCHEMBL24755152 | 0.79 | HDAC6 (1.00) | HDAC6HDAC2MAPTIRAK4TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-110407824-A | Aryl methanamide compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV ANHUI MEDICAL | 2019-11-05 | — | — | CN | disclosed |