Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721561 | 0.96 | PKM (0.62) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL28720510 | 0.91 | PKM (0.65) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL29513074 | 0.90 | PRSS1 (0.75) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL29513080 | 0.87 | PRSS1 (0.77) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL19451789 | 0.85 | PRSS1 (0.68) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL29154861 | 0.85 | KAT2B (0.64) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL29155059 | 0.85 | PRSS1 (0.55) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL29513025 | 0.85 | KMT2A (0.76) | PRSS1PKMKMT2AHCAR3KDM4E | |
| SCHEMBL19436444 | 0.84 | PRSS1 (0.64) | PRSS1PKMKMT2AHCAR3KDM4E | |
| Hydrochloric Acid SCHEMBL19436442 | 0.84 | PRSS1 (0.69) | PRSS1PKMKMT2AHCAR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417630-B | Modulators of interferon gene stimulating factor (STING) | 葛兰素史克知识产权开发有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114206882-A | Benzothiophene, thienopyridine, and thienopyrimidine derivatives for modulation of STING | CTXT私人有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113549110-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-109608443-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109071514-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-111417630-A | Modulators of interferon gene stimulating factor (STING) | 葛兰素史克知识产权开发有限公司 | 2020-07-14 | — | — | CN | disclosed |