Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602327 | 0.96 | PRSS1 (0.62) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL28720510 | 0.93 | PKM (0.65) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL29513074 | 0.88 | PRSS1 (0.75) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL29513080 | 0.88 | PRSS1 (0.77) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL29513025 | 0.86 | KMT2A (0.76) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL19451789 | 0.84 | PRSS1 (0.68) | PKMKMT2APRSS1KDM4EHCAR3 | |
| Hydrochloric Acid SCHEMBL28722113 | 0.84 | PRSS1 (0.68) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL22121284 | 0.83 | KMT2A (0.66) | PKMKMT2APRSS1KDM4EHCAR3 | |
| SCHEMBL19436444 | 0.83 | PRSS1 (0.64) | PKMKMT2APRSS1KDM4EHCAR3 | |
| Hydrochloric Acid SCHEMBL19436442 | 0.82 | PRSS1 (0.69) | PKMKMT2APRSS1KDM4EHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206882-A | Benzothiophene, thienopyridine, and thienopyrimidine derivatives for modulation of STING | CTXT私人有限公司 | 2022-03-18 | — | — | CN | disclosed |