Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CRHBP | P24387 | 2/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29513080 | 0.97 | PRSS1 (0.77) | PRSS1KMT2APKMKDM4EHCAR3 | |
| SCHEMBL19451789 | 0.95 | PRSS1 (0.68) | PRSS1KMT2APKMKDM4EHCAR3 | |
| SCHEMBL29513025 | 0.94 | KMT2A (0.76) | PRSS1KMT2APKMKDM4EHCAR3 | |
| Hydrochloric Acid SCHEMBL19436442 | 0.93 | PRSS1 (0.69) | PRSS1KMT2APKMKDM4EHCAR3 | |
| Hydrochloric Acid SCHEMBL28720410 | 0.93 | PRSS1 (0.69) | PRSS1KMT2APKMKDM4EHCAR3 | |
| SCHEMBL19436438 | 0.92 | PKM (0.67) | PRSS1KMT2APKMKDM4EHCAR3 | |
| SCHEMBL19436439 | 0.92 | PKM (0.67) | PRSS1KMT2APKMKDM4EHCAR3 | |
| Hydrochloric Acid SCHEMBL28722113 | 0.92 | PRSS1 (0.68) | PRSS1KMT2APKMKDM4EHCAR3 | |
| SCHEMBL19436444 | 0.91 | PRSS1 (0.64) | PRSS1KMT2APKMKDM4EHCAR3 | |
| SCHEMBL28602327 | 0.90 | PRSS1 (0.62) | PRSS1KMT2APKMKDM4EHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12384801-B2 | Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting | CTXT PTY LTD. (AU) | 2025-08-12 | — | — | US | disclosed |
| EP-3999185-B1 | BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING | CTXT PTY LTD (AU) | 2023-08-30 | — | — | EP | disclosed |
| US-20220389032-A1 | BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING | CTXT PTY LTD. (AU) | 2022-12-08 | — | — | US | disclosed |
| WO-2022177307-A1 | INTERFERON GENE STIMULATOR COMPOSITION COMPRISING BENZIMIDAZOLE DERIVATIVE AS ACTIVE INGREDIENT | 한국화학연구원 | 2022-08-25 | — | — | WO | disclosed |
| EP-3999185-A1 | BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING | CTXT Pty Limited (AU) | 2022-05-25 | — | — | EP | disclosed |
| CN-114206882-A | Benzothiophene, thienopyridine, and thienopyrimidine derivatives for modulation of STING | CTXT私人有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384801-B2 | Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting | STING1, CGAS, MAVS | PRSS1 2855/4885KMT2A 3255/4885PKM 3753/4885 |
| US-20220389032-A1 | BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING | STING1, CGAS, MAVS | PRSS1 2855/4885KMT2A 3255/4885PKM 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.