Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853269 | 0.91 | GCGR (0.41) | NPC1RAB9ATAAR1GAASMN1; SMN2 | |
| SCHEMBL2856396 | 0.91 | TAAR1 (0.46) | NPC1RAB9ATAAR1MEN1KMT2A | |
| SCHEMBL2857726 | 0.89 | TRPV1 (0.40) | TAAR1SMN1; SMN2MEN1KMT2AGCGR | |
| SCHEMBL2852169 | 0.89 | TRPV1 (0.38) | TAAR1GAAMEN1KMT2AGCGR | |
| SCHEMBL2862833 | 0.87 | NOTUM (0.38) | NPC1RAB9ATAAR1GCGRALDH1A1 | |
| SCHEMBL2852542 | 0.85 | GCGR (0.45) | TAAR1GCGRTRPV1 | |
| SCHEMBL2857531 | 0.85 | TAAR1 (0.52) | NPC1RAB9ATAAR1GAASMN1; SMN2 | |
| SCHEMBL2858437 | 0.83 | TAAR1 (0.42) | NPC1RAB9ATAAR1GAASMN1; SMN2 | |
| SCHEMBL2850489 | 0.76 | TAAR1 (0.53) | NPC1RAB9ATAAR1GAASMN1; SMN2 | |
| SCHEMBL2853284 | 0.76 | IDO1 (0.46) | NPC1RAB9ATAAR1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |