Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 9/20 | 0.41 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852714 | 0.86 | TAAR1 (0.48) | TAAR1FAAHDRD3DRD2CNR1 | |
| SCHEMBL2856396 | 0.86 | TAAR1 (0.46) | TAAR1DRD2CNR1TRPV1NPC1 | |
| SCHEMBL2852542 | 0.85 | GCGR (0.45) | TAAR1FAAHTRPV1 | |
| SCHEMBL2852169 | 0.84 | TRPV1 (0.38) | TAAR1FAAHDRD3DRD2CNR1 | |
| SCHEMBL2862833 | 0.84 | NOTUM (0.38) | TAAR1FAAHCNR1TRPV1NPC1 | |
| SCHEMBL2857726 | 0.84 | TRPV1 (0.40) | TAAR1CNR1TRPV1HDAC3HDAC1 | |
| SCHEMBL2853269 | 0.84 | GCGR (0.41) | TAAR1TRPV1NPC1GAARAB9A | |
| SCHEMBL2860245 | 0.83 | NPC1 (0.46) | TAAR1DRD3DRD2TRPV1NPC1 | |
| SCHEMBL2852329 | 0.81 | TAAR1 (0.49) | TAAR1TRPV1NPC1GAARAB9A | |
| SCHEMBL2855572 | 0.78 | TAAR1 (0.48) | TAAR1CNR1TRPV1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |