Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856396 | 0.92 | TAAR1 (0.46) | TRPV1ALDH1A1TAAR1HDAC3HDAC1 | |
| SCHEMBL2853269 | 0.90 | GCGR (0.41) | TRPV1ALDH1A1TAAR1HDAC3HDAC1 | |
| SCHEMBL2857726 | 0.90 | TRPV1 (0.40) | TRPV1ALDH1A1TAAR1HDAC3HDAC1 | |
| SCHEMBL2860245 | 0.89 | NPC1 (0.46) | TRPV1ALDH1A1TAAR1GCGRMEN1 | |
| SCHEMBL2862833 | 0.88 | NOTUM (0.38) | TRPV1ALDH1A1MGLLTAAR1HDAC3 | |
| SCHEMBL2852542 | 0.86 | GCGR (0.45) | TRPV1MGLLTAAR1GCGRGRM4 | |
| SCHEMBL2853130 | 0.85 | TAAR1 (0.45) | TRPV1ALDH1A1TAAR1HDAC3HDAC1 | |
| SCHEMBL2858437 | 0.84 | TAAR1 (0.42) | TRPV1ALDH1A1TAAR1HDAC3HDAC1 | |
| SCHEMBL2850489 | 0.77 | TAAR1 (0.53) | TRPV1ALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL2852329 | 0.77 | TAAR1 (0.49) | TRPV1ALDH1A1TAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |