Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853269 | 0.92 | GCGR (0.41) | TAAR1MEN1KMT2AALDH1A1GCGR | |
| SCHEMBL2857726 | 0.92 | TRPV1 (0.40) | TAAR1MEN1KMT2AALDH1A1GCGR | |
| SCHEMBL2852169 | 0.92 | TRPV1 (0.38) | TAAR1MEN1KMT2AALDH1A1GCGR | |
| SCHEMBL2860245 | 0.91 | NPC1 (0.46) | TAAR1MEN1KMT2AALDH1A1GCGR | |
| SCHEMBL2852542 | 0.90 | GCGR (0.45) | TAAR1GCGRTRPV1GRM4 | |
| SCHEMBL2862833 | 0.89 | NOTUM (0.38) | TAAR1ALDH1A1GCGRCNR1TRPV1 | |
| SCHEMBL2858437 | 0.86 | TAAR1 (0.42) | TAAR1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL2850489 | 0.85 | TAAR1 (0.53) | TAAR1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL2858248 | 0.79 | TAAR1 (0.45) | TAAR1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL2853130 | 0.79 | TAAR1 (0.45) | TAAR1MEN1KMT2AALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |