Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854509 | 0.94 | KDM4E (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL2854346 | 0.92 | MAPT (0.52) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL2855547 | 0.91 | TAAR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL2860715 | 0.90 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTLMNAPOLB | |
| SCHEMBL2863198 | 0.89 | CCR1 (0.50) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2852633 | 0.89 | TAAR1 (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL2856562 | 0.88 | MAPT (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL2860110 | 0.88 | KDM4E (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL2850321 | 0.88 | SMN1; SMN2 (0.47) | KDM4EALDH1A1MAPTLMNAPOLB | |
| SCHEMBL2852671 | 0.87 | MAPT (0.43) | KDM4EALDH1A1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |