Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854509 | 0.91 | KDM4E (0.50) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2852520 | 0.90 | TP53 (0.47) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2854586 | 0.90 | ALDH1A1 (0.47) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2859429 | 0.90 | NPC1 (0.46) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2854346 | 0.89 | MAPT (0.52) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2860253 | 0.89 | PLAAT3 (0.47) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2855547 | 0.88 | TAAR1 (0.54) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2852556 | 0.86 | TDP1 (0.44) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2859726 | 0.86 | ALDH1A1 (0.46) | TAAR1NPC1GAARAB9AALDH1A1 | |
| SCHEMBL2853389 | 0.86 | NPC1 (0.62) | TAAR1NPC1GAARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |