Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856562 | 0.96 | MAPT (0.48) | MAPTTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2863154 | 0.95 | MAPT (0.45) | MAPTTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2854509 | 0.94 | KDM4E (0.50) | MAPTTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2851231 | 0.93 | MAPT (0.46) | MAPTTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2860253 | 0.92 | PLAAT3 (0.47) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL2862820 | 0.91 | P2RX7 (0.45) | MAPTTSHRL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL2855547 | 0.91 | TAAR1 (0.54) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL2861752 | 0.91 | MAPT (0.43) | MAPTTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2854309 | 0.90 | MAPT (0.42) | MAPTTSHRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2850857 | 0.90 | TP53 (0.46) | MAPTTSHRL3MBTL1P2RX7TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |