Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859054 | 0.80 | POLB (0.71) | HPGDTSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL2854621 | 0.80 | TSHR (0.58) | CNR1HPGDCNR2TSHRLMNA | |
| SCHEMBL4236448 | 0.77 | CNR1 (0.59) | CNR1CNR2P2RX7 | |
| SCHEMBL2857918 | 0.76 | CCR1 (0.54) | HPGDLMNAKMT2ANPC1POLB | |
| SCHEMBL2723205 | 0.75 | LMNA (0.68) | CNR1HPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL2852175 | 0.75 | TACR1 (0.54) | HPGDLMNANPC1POLBKDM4E | |
| SCHEMBL17546622 | 0.72 | KLKB1 (0.58) | LMNASMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL14061476 | 0.72 | CNR1 (0.52) | CNR1HPGDCNR2TSHRSMN1; SMN2 | |
| SCHEMBL12499672 | 0.72 | RNASEH1 (0.43) | LMNAKMT2APOLBP2RX7MAPT | |
| SCHEMBL13753976 | 0.72 | KDM4E (0.69) | TSHRLMNASMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |