Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499730 | 0.86 | TSHR (0.44) | MAPTFPR2PROKR1PTGDR2P2RX7 | |
| SCHEMBL12499400 | 0.85 | VDR (0.49) | MAPTMEN1KMT2AHTTPOLB | |
| SCHEMBL12499272 | 0.83 | HCAR2 (0.45) | MAPTMEN1SLC26A4KMT2APOLB | |
| SCHEMBL12499865 | 0.83 | CCR2 (0.37) | RNASEH1CCR2HAO1MEN1SLC26A4 | |
| SCHEMBL12499826 | 0.83 | CCR2 (0.39) | RNASEH1CCR2HAO1KDM4AKDM5A | |
| SCHEMBL12499265 | 0.80 | SMN1; SMN2 (0.40) | PTGDR2POLBLMNA | |
| SCHEMBL12498729 | 0.76 | SRD5A2 (0.46) | PTGDR2GAAPOLBLMNA | |
| SCHEMBL12499850 | 0.73 | SMN1; SMN2 (0.41) | FPR2PROKR1 | |
| SCHEMBL12499589 | 0.73 | ALOX5 (0.43) | MAPTMEN1KMT2AGAAHTT | |
| SCHEMBL12499852 | 0.73 | PTGES (0.43) | MAPTKMT2AGAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |