SCHEMBL2860263

SCHEMBL2860263

CC1=CC([Zr](Cl)(Cl)(=C(c2ccccc2)c2ccccc2)C2c3cc(C)ccc3-c3ccc(C)cc32)c2c(C)cccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863958 0.90 HSP90AA1 (0.30)
SCHEMBL2860767 0.88
SCHEMBL2860436 0.88 LMNA (0.31)
SCHEMBL2871024 0.86 NPC1 (0.32) S1PR4NPC1RAB9A
SCHEMBL2867900 0.86 NPC1 (0.32) NPC1RAB9A
SCHEMBL2861631 0.86 NPC1 (0.33) NPC1RAB9A
SCHEMBL2861426 0.85 ALOX15 (0.31) S1PR4NPC1RAB9A
SCHEMBL2863298 0.84 NPC1 (0.32) NPC1RAB9A
SCHEMBL2870404 0.82 NPC1 (0.32) S1PR4NPC1RAB9A
SCHEMBL2862478 0.82 S1PR4 (0.32) S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed