SCHEMBL2860436

SCHEMBL2860436

CC1=CC([Zr](Cl)(Cl)(=C(c2ccccc2)c2ccccc2)C2c3cc(C(C)(C)C)ccc3-c3ccc(C(C)(C)C)cc32)c2c(C)cccc21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
KCNK9 Q9NPC2 1/20 0.31
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2868592 0.88 NPC1 (0.32) LMNAKCNK9
SCHEMBL2860263 0.88 S1PR4 (0.30)
SCHEMBL2863958 0.86 HSP90AA1 (0.30)
SCHEMBL2860945 0.86 ALDH1A1 (0.31) LMNAKCNK9
SCHEMBL2866152 0.85 KCNK3 (0.31) KCNK9
SCHEMBL2864152 0.85 KCNK3 (0.30) LMNAKCNK9
SCHEMBL2860767 0.84
SCHEMBL2867840 0.83 LMNA (0.32) LMNAKCNK9
SCHEMBL2863940 0.83 LMNA (0.31) LMNAKCNK9
SCHEMBL21980370 0.80 LMNA (0.31) LMNAKCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed