Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907776 | 0.85 | KDM4E (0.46) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL15211555 | 0.85 | KDM4E (0.46) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL27474726 | 0.83 | KDM4E (0.50) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL15995353 | 0.80 | SIRT2 (0.43) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| Hydrochloric Acid SCHEMBL28188402 | 0.79 | SIRT2 (0.42) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL9480589 | 0.79 | KDM4E (0.47) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL27905111 | 0.77 | KCNH2 (0.44) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL31182983 | 0.77 | KDM4E (0.46) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL15212887 | 0.77 | KDM4E (0.46) | SIRT2KDM4EALDH1A1CHRM5CHKA | |
| SCHEMBL4308808 | 0.77 | ALDH1A1 (0.50) | SIRT2KDM4EALDH1A1CHRM5CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087659-B | DMAP-thiourea catalyst and preparation method thereof, and high molecular weight biodegradable polyester and preparation method thereof | 中国科学院长春应用化学研究所 | 2022-07-19 | — | — | CN | disclosed |
| CN-113087659-A | DMAP-thiourea catalyst and preparation method thereof, and high molecular weight biodegradable polyester and preparation method thereof | 中国科学院长春应用化学研究所 | 2021-07-09 | — | — | CN | disclosed |