Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 8/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124776 | 0.88 | PTK6 (0.37) | PTK6LCKAURKBEGFRIGF1R | |
| SCHEMBL30402469 | 0.88 | PTK6 (0.37) | PTK6LCKAURKBEGFRIGF1R | |
| SCHEMBL24112346 | 0.86 | PTK6 (0.39) | PTK6LCKAURKBEGFRMAPKAPK5 | |
| SCHEMBL30385589 | 0.84 | PTK6 (0.45) | PTK6LCKAURKBEGFRMAPKAPK5 | |
| SCHEMBL24112347 | 0.84 | PTK6 (0.39) | PTK6LCKAURKBEGFRIGF1R | |
| Hydrochloric Acid SCHEMBL25176002 | 0.84 | PTK6 (0.45) | PTK6LCKAURKBEGFRMAPKAPK5 | |
| SCHEMBL28982214 | 0.82 | PTK6 (0.38) | PTK6LCKAURKBEGFR | |
| SCHEMBL22123725 | 0.82 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL30171867 | 0.82 | PTK6 (0.47) | PTK6LCKAURKB | |
| SCHEMBL22160965 | 0.82 | PTK6 (0.40) | PTK6LCKAURKBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195498-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113226469-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113195496-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113195498-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-113164771-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |