SCHEMBL28604281

SCHEMBL28604281

Cc1ccccc1C(C#N)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.54
ESR2 Q92731 4/20 0.54
SGMS2 Q8NHU3 2/20 0.42
MAOB P27338 1/20 0.40
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KIF20A O95235 1/20 0.39
SLC6A2 P23975 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
MAOA P21397 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21542930 0.83 ESR1 (0.46) ESR1ESR2SGMS2MEN1ALDH1A1
SCHEMBL27916171 0.79 SGMS2 (0.49) ESR1ESR2SGMS2MAOBALDH1A1
SCHEMBL1482971 0.79 IDO1 (0.41) ESR1ESR2MAOBMEN1ALDH1A1
SCHEMBL21632320 0.76 MEN1 (0.47) MEN1ALDH1A1KMT2ALMNAMAPT
SCHEMBL29090512 0.76 ACP3 (0.51) ESR1ESR2MEN1ALDH1A1KMT2A
SCHEMBL28606109 0.75 ESR2 (0.56) ESR1ESR2SGMS2MAOBMEN1
SCHEMBL8895327 0.75 TAAR1 (0.45) ESR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL56063 0.75 ESR2 (0.60) ESR1ESR2MAOBMEN1ALDH1A1
SCHEMBL21632003 0.75 ALDH1A1 (0.43) ESR1ESR2MEN1ALDH1A1KMT2A
SCHEMBL28618652 0.74 ESR2 (0.46) ESR1ESR2MAOBMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724891-B Mn-L manganese complex and preparation method and application thereof 浙江工业大学 2025-03-04 CN disclosed
CN-113713858-B Alpha alkylation reaction catalyst of nitrile and preparation method thereof 郑州大学 2023-06-23 CN disclosed
CN-113559939-B Alpha alkylation reaction catalyst of nitrile and preparation method thereof 郑州大学 2023-06-23 CN disclosed
CN-115724891-A Manganese complex Mn-L and preparation method and application thereof 浙江工业大学 2023-03-03 CN disclosed
CN-113713858-A Alpha alkylation reaction catalyst of nitrile and preparation method thereof 郑州大学 2021-11-30 CN disclosed
CN-113559939-A Alpha alkylation reaction catalyst for nitrile and preparation method thereof 郑州大学 2021-10-29 CN disclosed
CN-110026244-B Alpha alkylation reaction catalyst of nitrile and application thereof 郑州大学 2021-06-18 CN disclosed