Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 6/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035832 | 1.00 | L3MBTL1 (0.39) | L3MBTL1BRD4ATRATRIPPTPN11 | |
| SCHEMBL1935258 | 0.83 | L3MBTL1 (0.38) | L3MBTL1BRD4ATRATRIPPTPN11 | |
| SCHEMBL28917554 | 0.83 | ALDH1A1 (0.36) | L3MBTL1PKMKDM4EPDE4BHTR6 | |
| SCHEMBL1935252 | 0.83 | ALDH1A1 (0.36) | L3MBTL1PKMKDM4EPDE4BHTR6 | |
| SCHEMBL1935255 | 0.83 | ALDH1A1 (0.36) | L3MBTL1PKMKDM4EPDE4BHTR6 | |
| SCHEMBL1933799 | 0.81 | L3MBTL1 (0.47) | L3MBTL1BRD4PTPN11PKMKDM4E | |
| SCHEMBL27889757 | 0.81 | PIP4K2A (0.31) | — | |
| SCHEMBL28594637 | 0.81 | L3MBTL1 (0.43) | L3MBTL1BRD4PTPN11PKMKDM4E | |
| SCHEMBL12035853 | 0.81 | L3MBTL1 (0.43) | L3MBTL1BRD4PTPN11PKMKDM4E | |
| SCHEMBL18855917 | 0.80 | L3MBTL1 (0.46) | L3MBTL1BRD4PTPN11PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |