Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935255 | 1.00 | ALDH1A1 (0.36) | ALDH1A1GAAL3MBTL1PDE4BNOD2 | |
| SCHEMBL1935252 | 1.00 | ALDH1A1 (0.36) | ALDH1A1GAAL3MBTL1PDE4BNOD2 | |
| SCHEMBL20706502 | 0.87 | L3MBTL1 (0.39) | ALDH1A1GAAL3MBTL1PDE4BNOD2 | |
| SCHEMBL1933897 | 0.85 | KDM4E (0.40) | ALDH1A1GAAL3MBTL1PDE4BNOD2 | |
| SCHEMBL23061211 | 0.85 | NOD2 (0.40) | ALDH1A1GAAL3MBTL1PDE4BNOD2 | |
| SCHEMBL1935258 | 0.83 | L3MBTL1 (0.38) | ALDH1A1GAAL3MBTL1PDE4BNOD1 | |
| SCHEMBL27889781 | 0.83 | TP53 (0.40) | ALDH1A1L3MBTL1PDE4BTSHRLMNA | |
| SCHEMBL28604352 | 0.83 | L3MBTL1 (0.39) | L3MBTL1PDE4BHTR6MAPTKDM4E | |
| SCHEMBL12035832 | 0.83 | L3MBTL1 (0.39) | L3MBTL1PDE4BHTR6MAPTKDM4E | |
| SCHEMBL15203404 | 0.82 | L3MBTL1 (0.42) | ALDH1A1GAAL3MBTL1NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |