Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587573 | 0.89 | EPHX2 (0.37) | EPHX2MAOBKDM1AMAPTDRD2 | |
| SCHEMBL28479502 | 0.81 | JAK2 (0.41) | EPHX2MAOBKDM1AMAPTDRD2 | |
| SCHEMBL28576703 | 0.81 | L3MBTL1 (0.35) | MAPTDRD2KAT6AKMT2AL3MBTL1 | |
| SCHEMBL28476786 | 0.79 | KMT2A (0.40) | EPHX2MAOBKDM1AMAPTDRD2 | |
| SCHEMBL28789549 | 0.76 | CYP3A4 (0.37) | MAPTDRD2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28591857 | 0.75 | BRD4 (0.37) | EPHX2MAOBKDM1ADRD2CTSL | |
| SCHEMBL28421464 | 0.73 | CYP1A2 (0.48) | MAPTKMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL30890924 | 0.72 | EPHX2 (0.38) | EPHX2MAOBKDM1AMAPTDRD2 | |
| SCHEMBL28341524 | 0.72 | EPHX2 (0.48) | EPHX2MAOBKDM1AMAPTDRD2 | |
| SCHEMBL28597610 | 0.71 | RORC (0.38) | EPHX2MAOBKDM1ADRD2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778183-B | Nitrogen-containing ring derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-113166135-A | Benzothiophene derivative modulators, methods of making, and uses thereof | 上海翰森生物医药科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112778183-A | Nitrogen-containing ring derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-05-11 | — | — | CN | disclosed |