Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL2684565 | 0.96 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL19028065 | 0.96 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL2635292 | 0.96 | — | — | |
| Imidazole SCHEMBL1331920 | 0.96 | — | — | |
| Imidazole SCHEMBL1331382 | 0.96 | — | — | |
| Imidazole SCHEMBL30382963 | 0.96 | — | — | |
| Imidazole SCHEMBL28744226 | 0.96 | ALDH1A1 (1.00) | — | |
| Imidazole SCHEMBL897 | 0.96 | — | — | |
| Imidazole SCHEMBL3240045 | 0.93 | — | — | |
| Imidazole SCHEMBL553108 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970501-B | New preparation method of 1, 2-diphenylethane | 三峡大学 | 2021-07-13 | — | — | CN | disclosed |